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Research

News about research advances, awards, and more.

Unprecedented Compound Takes a Step Toward Breast Cancer Clinical Trials

Estrogen receptor-positive breast cancer is the most common form of breast cancer, affecting approximately 75 percent of breast cancer patients. In advanced and metastatic form, it is lethal, claiming the lives of nearly 350,000 individuals annually. Presently, no drug is able to eradicate these...

Chen lab uncovers new insights, new player in immune system defense

When confronted with infection or injury, our body rallies to fight and heal itself and inflammation is a key part of this early defense system. But inflammation can also go awry, as exhibited in chronic illnesses such as obesity and type 2 diabetes. Biochemistry professor...

Researchers investigate how human stomach cells recognize and minimize damage to mitochondria during H. pylori infection

University of Illinois researchers have elucidated a mechanism whereby gastric cells detect and respond to toxin infiltration within the cell’s powerhouse, the mitochondria. The Blanke lab, within the Department of Microbiology in the School of Molecular & Cellular...

New research from Raetzman lab, led by undergraduate, investigates the mechanism behind genetic cause of congenital hypopituitarism 

Hypopituitarism occurs when the pituitary gland, a small, pea-sized gland at the base of the brain, does not make enough hormones that are essential for growth, metabolism, and reproduction.  Lori Raetzman, a professor of...

“Buckle up and hold on tight!” Study discovers how bacterial pathogens stick to surfaces better when they encounter fluid flow

Host tissues and medical devices are ideal surfaces for bacterial pathogens to colonize and infect. Fluid flow is thought to flush bacteria off these surfaces, but University of Illinois researchers have found that some bacteria can strengthen their adhesion to the surface when flow is applied. In...

Sweeney Lab demonstrates how neurons with melanocortin-3 receptor regulate anxiety-related behavior

In a new study, University of Illinois scientists have shown how a specific group of neurons respond to information about an animal’s energy state and external challenges to regulate anxiety, fear, and similar behavior. The findings, published in the Journal of Neuroscience, suggest these...

Xinzhu Yu receives NIH Director's New Innovator Award

Xinzhu Yu, a professor of molecular and integrative physiology in the School of Molecular & Cellular Biology, is a recipient of the National...

Research sheds light on molecular pathway driving muscle weakness in muscular dystrophy

University of Illinois researchers have uncovered a molecular mechanism that influences muscle weakness in a mouse model of Duchenne Muscular Dystrophy, the most common inherited neuromuscular disease and one of the most severe forms of inherited muscular dystrophies. The genetic disorder causes...

Protein p53 regulates learning, memory, sociability in mice

University of Illinois researchers have established the protein p53 as critical for regulating sociability, repetitive behavior, and hippocampus-related learning and memory in mice, illuminating the relationship between the protein-coding gene TP53 and neurodevelopmental and psychiatric disorders...

Meet new biochemistry professor Chu-Young Kim

The School of Molecular & Cellular Biology and Department of Biochemistry are pleased to welcome Chu-Young Kim as a professor of biochemistry. We recently spoke with him about his research and teaching...