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Alzheimer's disease

Neuronal Excitability in Health and Disease

A new era has dawned in understanding neuropathological disorders such as epilepsy, schizophrenia, depression, and autism spectrum disorders. These disorders, traditionally classified in the Diagnostic and Statistical Manual of Mental Disorders by the American Psychiatric Society, are now being re-...

Synaptic Membrane Nanodiscs May Help Find Alzheimer’s Disease Therapeutics

Congratulations to Stephen Sligar for his recent publication in PLoS One: “Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen that Targets Binding Sites for Alzheimer’s-Associated Aβ Oligomers.” Using a High Throughput Screening (HTS) facility at NU, Sligar and colleagues...

MCB Director's Seminar

On November 18 at this year's MCB Director's Seminar, special guest Northwestern University Professor of Neurobiology William L. Klein delivered the talk: "Synaptotoxic AΒ Oligomers (ADDLs): A Molecular Basis for the Cause, Diagnosis and Treatment of Alzheimer's Disease."